Unlike Shops, where Isaac pays with money, to make Deals with the Devil Isaac has to trade Red Heart Containers as payment. If a Devil Room appears upon defeating Mom's Heart or It Lives, it will only contain a trapdoor to Sheol.Ī Devil Room has a high chance of spawning items that will be put up for sale. Some regular enemies can appear as well, including:ġ Mom's Hand, 2 Nulls, 1 Imp, or 1 Mom's Dead Hand. Spikes may spawn instead of or in addition to any items/pickups.
3 Conditions to Make Devil Rooms Appear.